I'm not that familiar with anything east of the big river, but the first question would be who holds the mineral rights to the property in question?
If the landowner, then in all probability they would fall under state laws and regulations. USFS would have no jurisdiction over private property, unless the feds still have the mineral rights. The big issue would be water quality as it enters federal ground, but as long as it meets state standards as it leaves the private ground it should be alright.
Need to check with USFS and the state/county to cover all the bases as to mineral ownership and laws/regs pertaining to mining/prospecting.
Good luck, here's hoping you are able to find something worthwhile.